报告题目:Modeling oscillations: My journey through biological rhythms

报告时间:2023年8月2日10:00-11:00

报告地点:金融工程研究中心105学术报告厅

报告人:Albert Goldbeter,布鲁塞尔自由大学

报告摘要:Oscillations abound in biological systems and generally correspond to the evolution to a unique limit cycle. Over decades my work has primarily been devoted to modeling the molecular mechanism of a variety of cellular rhythms such as glycolytic oscillations in yeast, cAMP oscillations and waves in social amoebae, Ca++ oscillations, the segmentation clock responsible for somite formation in the course of development, circadian clocks in Drosophila and mammals, the cell cycle in amphibian embryos and in mammalian cells, and the coupling between the cell cycle and the circadian clock. I will discuss how, and why, the analysis of one system led to the next among these oscillatory phenomena. Another line of research pertains to the transition from simple periodic behavior to complex oscillations including chaos and the coexistence between multiple stable limit cycles (multi-rhythmicity). The mathematical modeling of these oscillatory phenomena shows how biological rhythms display common properties in spite of marked differences in their period and molecular mechanism

  

  

报告人简介: Albert Goldbeter教授是比利时布鲁塞尔自由大学(Université libre de Bruxelles,简称ULB)的杰出教授,比利时皇家科学院院士。Goldbeter教授以在数学生物学和系统生物学领域的贡献而闻名,专注于生物节律和振荡的研究,在昼夜节律、细胞周期调控和生化信号网络的机制方面做出了重要贡献。Goldbeter教授发表了许多有影响力的论文,并在系统生物学领域撰写了多本书籍。他的研究获得了国际认可,并对生物过程的理解产生了深远影响。

邀请人: 颜洁